Prospective Study of SerumAdiponectin and IncidentMetabolic Syndrome The ARIRANG Study
نویسندگان
چکیده
RESULTSdDuring an average of 2.6 years of follow-up, 153 men (18.4%) and 199 women (16.4%) developed metabolic syndrome. In multivariable-adjusted models, the odds ratio for incident metabolic syndrome comparing the highest with the lowest quartiles of adiponectin levels was 0.25 (95% CI 0.14–0.47) in men and 0.45 (0.28–0.74) in women. While serum adiponectin did not improve the area under the ROC curve for predicting new-onset metabolic syndrome based on information from metabolic syndrome components, the net reclassification improvement and the integrated discrimination improvement of prediction models including adiponectin were significantly higher compared with those of models not including adiponectin among men, with a significant difference between men and women (P = 0.001).
منابع مشابه
Response to Comment on: Kim et al. Prospective Study of Serum Adiponectin and Incident Metabolic Syndrome: The ARIRANG Study. Diabetes Care 2013;36:1547–1553
We thank Dr. Kawada (1) for his comments in response to the ARIRANG study findings on the predictive ability of adiponectin for metabolic syndrome (2). Dr. Kawada raised concerns about the appropriateness of logistic regression because there was some variability in the follow-up times of study participants even though the follow-up period was relatively short (median 2.4 years, interquartile ra...
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